I'm looking at getting a road bike to supplement my all-purpose Trek 7.1FX. Here are the ones I like in order of preference. They are all expensive but well worth it.
Jamis Xenith ~$1800
This one has a carbon fiber composite frame and full carbon fork. DC19 wheels with Zaffiro 700c tires. Derailleur and shifters are Shimano.
Trek Madone 6.7SSL (custom) ~$6700
This is from Trek's site where you can make your own. Composite frame, mostly SRAM and Bontrager.
Look 566 105 ~$3000
The frame is a special mix and made with a unique process. Everything on the bike is Shimano.
Time VRS Vibraser ~$5000
A full carbon frame and fork. All of the major stuff is SRAM and Time makes their own pedals, stems and wheels.
Tough choices...